Molecular Neuropathology Laboratory

The Molecular Neuropathology Laboratory is the designated laboratory within the South East Genomics Laboratory Hub (SEGLH) offering molecular analysis of neurological malignancies as part of the NHSE Genomics Medicine Service. The laboratory carries out approximately 800 molecular neuropathology tests per year. These include DNA and RNA testing of common brain tumour prognostic markers such as MGMT promoter methylation status and methylation array.

Laboratory overview

The laboratory operates 8:30am to 5pm, Monday to Friday.

The laboratory delivers a range of tests for neurological malignancies, all of which was aligned to the NHSE Genomics Test Directory (https://www.england.nhs.uk/publication/national-genomic-test-directories/).

MGMT promoter methylation status- 14 days from sample receipt

Methylation array- 21 days from sample receipt

Multimodal NGS panel- 21 days from sample receipt

Whole genome sequencing- 42 days from receipt of data

Requests

Our current request form is available to download from the KCH website: https://www.kch.nhs.uk/gps-and-referrers/neuropathology-guides-for-referrers/molecular-neuropathology-service/

If you have insufficient material or if you require multiple tests on the same samples, please call the laboratory to discuss any additional requirements prior to sending.

User handbook

A copy of the department's User Handbook is available below.