Beta-2 Microglobulin

Description: 
The measurement of beta-2 microglobulin is used as prognostic indicator in myeloma. Concentrations will also be raised in patients with renal dysfunction.
Clinical details: 
Beta-2 microglobulin is a low molecular weight protein (11-12 kDa) found on the surface of all human cells as a component polypeptide chain of the HLA antigen complex. It is found in most body fluids and can be measured in serum, CSF, saliva, joint fluids and urine. The protein is excreted through the renal glomerulus, the majority being reabsorbed in the proximal tubules.
Related condition or disease: 
Multiple Myeloma, Malignancy, Renal Transplant, Collagen Vascular Disorders.
Reference range: 

0.8 - 2.34 mg/L

Units: 
mg/L
Department: 
Diagnostic Immunology and Allergy Department
Location: 
Blackfriars Hub
Sample type and Volume required: 
Clotted (yellow SST tube). Serum.
Turnaround time: 
3 days
Criteria for acceptance / rejections of sample
Contacts:
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Diagnostic Immunology Laboratory at Blackfriars Hub

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Last updated: 21/04/2026