Tissue Transglutaminase (TTG)

Description: 
IgA anti-TTG autoantibodies is a highly specific and sensitive antibody test in the diagnosis of coeliac disease. The antibody becomes negative a few months after starting gluten free diet. It can also be used to monitor compliance with a gluten free diet. In IgA deficient patients IgG endomysial is tested for. IgG TTG is at present not available.
Related condition or disease: 
Coeliac disease.
Reference range: 

<7.

Units: 
IU/ml.
Location: 
King's College Hospital
Sample type and Volume required: 
Clotted (Gold top vacutainer)

Call in advance: 
If urgent.
Turnaround time: 
6 Days.
Special sample instructions: 

All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.

Criteria for acceptance / rejections of sample
Storage and transport: 
Serum stored at 4°C should be sent by first class post.
Time limit for extra tests: 
10 Days.
Contacts:
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Diagnostic Immunology Laboratory at King's

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Last updated: 23/05/2023