Beta 2 Glycoprotein1 antibodies

Anti-β2GPI is an antiphospholipid antibody that is associated with the antiphospholipid antibody syndrome (APS). This antibody is tested in conjunction with IgG and IgM anti-cardiolipin antibody and lupus anticoagulant (done in the Coagulation laboratory).Anti-β2GPI must be detected on 2 more occasions at least 12 weeks apart to fulfil the laboratory diagnostic criteria for APS. It may also be positive following an infection.
Reference range: 

Beta 2 glycoprotein 1 IgG <10
Beta 2 glycoprotein 1 IgM <10

Sample type and Volume required: 
Clotted (Gold top vacutainer) 4 ml
Turnaround time: 
14 days
Special sample instructions: 

All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.

Storage and transport: 
Serum stored at 4°C should be sent by first class post
Time limit for extra tests: 
10 days
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 20/04/2023