E. coli 0157 Serology

This test is referred to another lab outside our network
This does not affect where samples are sent and where your results are issued.
Sample sent to PHE Colindale GBRU referral laboratory for testing for the presence of antibodies to the lipopolysaccharide of Vero cytotoxin producing Escherichia coli (VTEC) O157 and a limited number of other VTEC. This may be helpful in the diagnosis of a clinical syndrome, such as Haemolytic Uraemic syndrome (HUS) or Thrombotic thrombocytopenia purpura, suggestive of a recent infection with a VTEC organism. Direct isolation of the organism from a suitable culture is the most convincing diagnostic tool but may not be possible by the time patients present with HUS. Please Note: If a patient has undergone renal dialysis or received a blood transfusion, this can adversely affect tests for detecting antibodies to E. coli 0157. Please provide information on request if any of these treatments have been performed. This assay is available routinely Mon to Fri.
Clinical details: 
E. coli O157 and other VTEC are associated with cases of gastroenteritis and dysentry and in upto 10% of cases are complicated by haemoytic uraemic syndrome in the period following the gastroenteritis.
Sample type and Volume required: 
2.5 – 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Turnaround time: 
14 working days
Storage and transport: 
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730

For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 04/12/2017