Intrinsic Factor Antibody

In addition to anti-gastric parietal cell antibody another autoantibody is present in up to 70% of individuals with pernicious anemia, anti-intrinsic factor (IF) antibody. Two types of anti-IF are described; one blocks the binding of vitamin B12 to intrinsic factor and the other binds to intrinsic factor and intrinsic factor vitamin B12 complex preventing absorption of the vitamin.
Reference range: 


Negative - Positive
Sample type and Volume required: 
Clotted (Gold top vacutainer)
Turnaround time: 
21 days
Storage and transport: 
Serum stored at 4ºC should be sent by 1st class post as soon as possible
Time limit for extra tests: 
10 days
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 20/04/2023