Paliperidone

Description: 
Detection of 9-hydroxyrisperidone by LC-MS/MS
Clinical details: 
Therapeutic drug monitoring - adherence to medication, dose optimisation, drug toxicity
Related condition or disease: 
Antipsychotic medication used to treat schizophrenia used to treat mania, and as maintenance for bipolar disorder (at lower doses)
Reference range: 

Interpretive comments are given on the report

Synonyms or keywords: 
9-hydroxyrisperidone
Units: 
µg/L
Department: 
Toxicology Department
Location: 
King's College Hospital
Sample type and Volume required: 
4 mL EDTA whole blood or 2 mL plasma or serum (pre-dose or ‘trough’ sample). Please avoid gel-separator tubes
Turnaround time: 
5 working days
Criteria for acceptance / rejections of sample
Storage and transport: 
Please refrigerate (if possible) if not sending immediately. Send by first class post.
Contacts:
Toxicology Department at King's Hospital
020 3299 5881
kch-tr.toxicology@nhs.net
King's College Hospital
Bessemer Wing - 3rd Floor
Denmark Hill
London SE5 9RS
Therapeutic Drug Monitoring at Blackfriars Hub
0204 591 0056 or 0204 591 0054
toxicologystaff@synnovis.co.uk
1st floor Synnovis, Friars Bridge Court, 41-43 Blackfriars Road, London, SE1 8NZ
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Therapeutic Drug Monitoring Laboratory at Blackfriars Hub
Antipsychotic Drug Assay Request Form
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Last updated: 23/01/2026