Epstein-barr Virus (EBV) Viral Load

Quantitative real -time polymerase chain reaction (PCR) assay for the quantification of Epstein-Barr Virus (EBV) DNA in EDTA whole blood. Used to monitor transplant patients for primary or reactivated EBV infection and to elucidate suspected primary EBV infection in immunocompetent individuals. In very specific situations it can be used to monitor patients with EBV-associated tumours. This assay is available routinely Mon and Thurs.
Clinical details: 
- Post transplant surveillance
- Glandular fever
- Mononuclear syndrome
- Infectious mononucleosis
- meningitis/encephalitis
- Jaundice /hepatitis
- hepatomegaly
- splenomegaly
- splenic rupture
- chronic active EBV infection
- Burkitt's lymphoma
- nasopharyngeal carcinoma
- AIDS-associated lymphoma
- primary CNS lymphoma
- hodgkin’s disease
- non-Hodgkin's lymphoma
- post-transplant lymphoproliferative diseases (PTLD)
Reference range: 

311 to 10,000,000 IU/mL

Synonyms or keywords: 
- post transplant surveillance - infectous mononucleosis - chronic active EBV infection
International units per milliliter (IU/mL).
Sample type and Volume required: 
4-9ml Purple Top EDTA whole blood.
Turnaround time: 
7 working days
Storage and transport: 
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). Samples should be sent to CSR promptly as the sensitivity of assays that detect RNA/DNA depend on sample quality/integrity. Please store samples in a refrigerator if there is a delay in sending samples to CSR.
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730

For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 06/10/2023